HADH antibody (AA 57-314)
Quick Overview for HADH antibody (AA 57-314) (ABIN2468091)
Target
See all HADH AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 57-314
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Purification
- Immunoaffinity Purified
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Application Notes
- Short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial antibody can be used for the detection of Short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial by Western Blot.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline. No preservatives added.
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Preservative
- Without preservative
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Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage
- 4 °C/-20 °C
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Storage Comment
- HADHSC antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))
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Alternative Name
- HADHSC
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Background
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FUNCTION: Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA.
DISEASE: Defects in HADHSC are the cause of 3-alpha-hydroxyacyl-CoA dehydrogenase deficiency (HAD deficiency) [MIM:609609]. HAD deficiency is a metabolic disorder with various clinical presentations including hypoglycemia, hepatoencephalopathy, myopathy or cardiomyopathy, and in some cases sudden death. -
Molecular Weight
- 34.3 kDa (calculated)
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Gene ID
- 3033
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NCBI Accession
- NP_005318
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UniProt
- Q16836
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Pathways
- Negative Regulation of Hormone Secretion, Monocarboxylic Acid Catabolic Process
Target
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