BRS3 antibody (2nd Extracellular Domain)

Catalog No. ABIN2469295

This Rabbit Polyclonal antibody specifically detects BRS3 in IHC. It exhibits reactivity toward Human, Gibbon and Gorilla.

Quick Overview for BRS3 antibody (2nd Extracellular Domain) (ABIN2469295)

Target: BRS3 (Bombesin-Like Receptor 3 (BRS3))

Reactivity: Human, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRS3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-BRS3 Antibody

Binding Specificity: 2nd Extracellular Domain

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CNNM2 (45 % ).

Purification: Immunoaffinity Chromatography

Immunogen: BRS3 antibody was raised against a peptide located in the 2nd extracellular domain of BRS3 (Human).

Application Details

Application Notes: BRS3 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 10 μg/mL, immunocytochemistry, and immunoprecipitation.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: BRS3 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for BRS3

Target: BRS3 (Bombesin-Like Receptor 3 (BRS3))

Alternative Name: BRS3

Background: BRS3 is classified as an Orphan-A Receptor and is highly similar to the bombesin receptors but has a very low affinity for bombesin itself. Mice lacking BRS3 develop metabolic defects and obesity, suggesting that BRS3 may be an important target for obesity research. In addition, BRS3 may be involved in diabetes and hypertension.

Gene ID: 680

UniProt: P32247

Pathways: Feeding Behaviour