PTPRM antibody (Internal Region)

Catalog No. ABIN2469323

Product Details anti-PTPRM Antibody

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Rabbit, Horse, Hamster, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRM antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: PTPRM antibody was raised against a peptide located near the internal domain of PTPRM (Human).

Application Details

Application Notes: PTPRM antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 - 10 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: PTPRM antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for PTPRM

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Alternative Name: PTPRM (PTPRM Products)

Background: PTP mu, a R2A receptor protein tyrosine phosphatase, is composed of an extracellular segment containing a MAM domain, an immunoglobulin domain and four fibronectin type III repeats, a transmembrane segment, and two intracellular protein phosphatase domains. PTP mu has been shown to affect cell-cell aggregation, regulate cardiac myocyte Kv1.5 channel expression, and promote neurite outgrowth of retinal ganglion cells. The human PTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer. PTP mu may be important in responses to pathological conditions associated with the loss of cell-cell interactions in the heart.

Gene ID: 5797

UniProt: P28827