PTPRM antibody (AA 565-742)

Catalog No. ABIN5684049

This Mouse Monoclonal antibody specifically detects PTPRM in ELISA. It exhibits reactivity toward Human.

Quick Overview for PTPRM antibody (AA 565-742) (ABIN5684049)

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTPRM antibody is un-conjugated

Application: ELISA

Clone: 1H6D10

Product Details anti-PTPRM Antibody

Binding Specificity: AA 565-742

Purpose: PTPRM Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PTPRM (AA: 565-742) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PTPRM

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Alternative Name: PTPRM

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Molecular Weight: 163.7 kDa

Gene ID: 5797

UniProt: P28827