PTPRM antibody

Catalog No. ABIN7238327

The Rabbit Polyclonal anti-PTPRM antibody is suitable to detect PTPRM in samples from Human and Mouse. It has been validated for ELISA and IHC.

Quick Overview for PTPRM antibody (ABIN7238327)

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRM antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PTPRM Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human PTPRM

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRM

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Alternative Name: PTPRM

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

NCBI Accession: NP_002836

UniProt: P28827