Glucagon antibody (AA 19-29)

Catalog No. ABIN2473807

This Sheep Polyclonal antibody specifically detects Glucagon in RIA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Glucagon antibody (AA 19-29) (ABIN2473807)

Target: Glucagon (GCG)

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This Glucagon antibody is un-conjugated

Application: Radioimmunoassay (RIA)

Product Details anti-Glucagon Antibody

Binding Specificity: AA 19-29

Specificity: This antibody is specific for the C terminal of Glucagon, a linear peptide of 29 amino acids. Its primary sequence is highly conserved among vertebrates.

Characteristics: Purified IgG

Purification: Purified

Immunogen: Glucagon amino acids 19-29, prepared by enzymatic cleavage of Porcine glucagon, conjugated with bovine thyroglobulin carrier protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5.0 mg/mL

References for anti-Glucagon antibody (ABIN2473807)

Figueroa, Hess, Ky, Brown, Sandig, Hermanowski-Vosatka, Twells, Todd, Austin: "Expression of the type I diabetes-associated gene LRP5 in macrophages, vitamin A system cells, and the Islets of Langerhans suggests multiple potential roles in diabetes." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 48, Issue 10, pp. 1357-68, (2000) (PubMed).

Target Details for Glucagon

Target: Glucagon (GCG)

Alternative Name: GLUCAGON

Gene ID: 2641

UniProt: P01275

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling