CCL2 antibody

Catalog No. ABIN2475529

This Mouse Monoclonal antibody specifically detects CCL2 in WB, ELISA, IP, IHC (p), FACS and IHC (fro). It exhibits reactivity toward Human, Rhesus Monkey and Cynomolgus and has been mentioned in 3+ publications.

Quick Overview for CCL2 antibody (ABIN2475529)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivity: Human, Rhesus Monkey, Cynomolgus

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 5D3-F7

Product Details anti-CCL2 Antibody

Cross-Reactivity: Cynomolgus, Rhesus Monkey

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

References for anti-CCL2 antibody (ABIN2475529)

Karrer, Bosserhoff, Weiderer, Distler, Landthaler, Szeimies, Müller-Ladner, Schölmerich, Hellerbrand: "The -2518 promotor polymorphism in the MCP-1 gene is associated with systemic sclerosis." in: The Journal of investigative dermatology, Vol. 124, Issue 1, pp. 92-8, (2005) (PubMed).

Rezaie-Majd, Maca, Bucek, Valent, Müller, Husslein, Kashanipour, Minar, Baghestanian: "Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 22, Issue 7, pp. 1194-9, (2002) (PubMed).

Corrigall, Arastu, Khan, Shah, Fife, Smeets, Tak, Panayi: "Functional IL-2 receptor beta (CD122) and gamma (CD132) chains are expressed by fibroblast-like synoviocytes: activation by IL-2 stimulates monocyte chemoattractant protein-1 production." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 6, pp. 4141-7, (2001) (PubMed).

Target Details for CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: MCP-1

Background: Synonyms: CCL2

Gene ID: 6347

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection