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PARP1 antibody

PARP1 Reactivity: Human, Mouse, Rat, Drosophila melanogaster, Hamster, Xenopus laevis WB, ELISA, IP, IF, IHC (p), IHC (fro) Host: Mouse Monoclonal A6-4-12 unconjugated
Catalog No. ABIN2476185
  • Target See all PARP1 Antibodies
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Reactivity
    • 217
    • 55
    • 42
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Drosophila melanogaster, Hamster, Xenopus laevis
    Host
    • 213
    • 21
    • 1
    Mouse
    Clonality
    • 206
    • 29
    Monoclonal
    Conjugate
    • 133
    • 16
    • 15
    • 13
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PARP1 antibody is un-conjugated
    Application
    • 146
    • 117
    • 69
    • 32
    • 31
    • 25
    • 24
    • 22
    • 20
    • 17
    • 16
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Fruit Fly (Drosophila melanogaster), Hamster, Mouse (Murine), Rat (Rattus), Xenopus laevis
    Characteristics
    Purified IgG
    Purification
    Purified
    Clone
    A6-4-12
    Isotype
    IgG1
    Top Product
    Discover our top product PARP1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
  • Pinton, Manente, Murer, De Marino, Mutti, Moro: "PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." in: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, (2013) (PubMed).

    Harris, Jakob, Taucher-Scholz, Dianov, Becherel, Lavin: "Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage." in: Human molecular genetics, Vol. 18, Issue 21, pp. 4102-17, (2009) (PubMed).

    Freire, dAdda Di Fagagna, Wu, Pedrazzi, Stagljar, Hickson, Jackson: "Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha." in: Nucleic acids research, Vol. 29, Issue 15, pp. 3172-80, (2001) (PubMed).

  • Target
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Alternative Name
    POLY(ADP-RIBOSE) POLYMERASE-1 (PARP1 Products)
    Gene ID
    142
    UniProt
    P09874
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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