PARP1 antibody (Poly (ADP-Ribose) Polymerase 1)

Details for Product anti-PARP1 Antibody No. ABIN2476185
Antigen
  • ADPRT
  • ADPRT 1
  • ADPRT1
  • ARTD1
  • PARP
  • PARP-1
  • PPOL
  • pADPRT-1
  • Adprt
  • Parp-1
  • 5830444G22Rik
  • AI893648
  • Adprp
  • Adprt1
  • C80510
  • parp-1
  • sPARP-1
  • BEST:LD21673
  • CG17685
  • CG17696
  • CG17718
  • CG40411
  • D.PARP
  • Dm.pARTa
  • Dmel\\CG40411
  • LD21673.3prime
  • PARP1
  • dPARP
  • parp
  • adprt1
  • padprt-1
  • ppol
  • si:dkey-206f10.3
  • wu:fc60f12
  • zgc:110092
  • poly(ADP-ribose) polymerase 1
  • poly (ADP-ribose) polymerase 1
  • poly (ADP-ribose) polymerase family, member 1
  • Poly-(ADP-ribose) polymerase
  • poly(ADP-ribose) polymerase 1 L homeolog
  • PARP1
  • Parp1
  • Parp
  • parp1.L
  • parp1
Reactivity
Fruit Fly (Drosophila melanogaster), Hamster, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
536
179
144
18
16
12
9
9
6
6
5
3
2
2
1
1
1
1
1
1
1
Host
Mouse
490
88
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This PARP1 antibody is un-conjugated
33
27
25
25
25
24
9
9
9
9
9
9
3
3
3
3
3
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
340
277
159
90
46
46
40
40
37
27
21
8
6
5
4
3
2
1
1
Options
Clone A6-4-12
Isotype IgG1
Cross-Reactivity Fruit Fly (Drosophila melanogaster), Hamster, Mouse (Murine), Rat (Rattus), Xenopus laevis
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others PARP1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name POLY(ADP-RIBOSE) POLYMERASE-1 (PARP1 Antibody Abstract)
Gene ID 142
UniProt P09874
Pathways Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Supplier Images
Image no. 1 for anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody (ABIN2476185) anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody
Product cited in: Pinton, Manente, Murer, De Marino, Mutti, Moro: "PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." in: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, 2013 (PubMed).

Harris, Jakob, Taucher-Scholz, Dianov, Becherel, Lavin: "Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage." in: Human molecular genetics, Vol. 18, Issue 21, pp. 4102-17, 2009 (PubMed).

Freire, dAdda Di Fagagna, Wu, Pedrazzi, Stagljar, Hickson, Jackson: "Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha." in: Nucleic acids research, Vol. 29, Issue 15, pp. 3172-80, 2001 (PubMed).

Did you look for something else?