PARP1 antibody
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- Target See all PARP1 Antibodies
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Reactivity
- Human, Mouse, Rat, Drosophila melanogaster, Hamster, Xenopus laevis
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PARP1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Fruit Fly (Drosophila melanogaster), Hamster, Mouse (Murine), Rat (Rattus), Xenopus laevis
- Characteristics
- Purified IgG
- Purification
- Purified
- Clone
- A6-4-12
- Isotype
- IgG1
- Top Product
- Discover our top product PARP1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
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PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." in: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, (2013) (PubMed).
: "Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage." in: Human molecular genetics, Vol. 18, Issue 21, pp. 4102-17, (2009) (PubMed).
: "Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha." in: Nucleic acids research, Vol. 29, Issue 15, pp. 3172-80, (2001) (PubMed).
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PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." in: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, (2013) (PubMed).
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- Target
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
- Alternative Name
- POLY(ADP-RIBOSE) POLYMERASE-1 (PARP1 Products)
- Gene ID
- 142
- UniProt
- P09874
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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