TGF-beta antibody

Catalog No. ABIN2476753

This Rabbit Polyclonal antibody specifically detects TGF-beta in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Rabbit and Mammalian and has been mentioned in 3+ publications.

Quick Overview for TGF-beta antibody (ABIN2476753)

Target: TGF-beta (TGFb)

Reactivity: Human, Mouse, Rat, Rabbit, Mammalian

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGF-beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TGF-beta Antibody

Cross-Reactivity: Mammalian, Mouse (Murine), Rabbit, Rat (Rattus)

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

References for anti-TGF-beta antibody (ABIN2476753)

Polichnowski, Lan, Geng, Griffin, Venkatachalam, Bidani: "Severe renal mass reduction impairs recovery and promotes fibrosis after AKI." in: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 7, pp. 1496-507, (2014) (PubMed).

Moore, Sawyer, Charokopos, Skokos, Kyriakides: "Loss of monocyte chemoattractant protein-1 alters macrophage polarization and reduces NF?B activation in the foreign body response." in: Acta biomaterialia, Vol. 11, pp. 37-47, (2014) (PubMed).

Geng, Lan, Singha, Gilchrist, Weinreb, Violette, Weinberg, Saikumar, Venkatachalam: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).

Target Details for TGF-beta

Target: TGF-beta (TGFb)

Alternative Name: TGF beta

Background: Synonyms: TRANSFORMING GROWTH FACTOR BETA

Gene ID: 7040

UniProt: P01137

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus