tyrosine Hydroxylase (TH) (pSer40) antibody

Details for Product No. ABIN2477021
Antigen
  • DYT14
  • DYT5b
  • TYH
  • The
  • CG10118
  • DH65B
  • DTH
  • Dmel\\CG10118
  • Pale
  • Ple
  • TH
  • Th
  • VII
  • dTH1
  • dTH65B
  • pale/ple
  • th
  • dyt14
  • dyt5b
  • tyh
  • tyrosine hydroxylase
  • pale
  • tyrosine 3-monooxygenase
  • tyrosine hydroxylase S homeolog
  • TH
  • Th
  • ple
  • th
  • th.S
Epitope
pSer40
41
30
30
24
16
14
5
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
245
225
173
18
17
15
10
10
5
3
3
3
3
2
2
2
1
1
1
1
Host
Rabbit
246
50
15
10
9
Clonality
Polyclonal
Conjugate
Un-conjugated
10
6
6
6
6
6
6
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
262
178
129
64
51
36
35
31
27
13
11
7
6
3
3
2
Options
Immunogen Synthetic phosphopeptide corresponding to an amino acid sequence within Tyrosine Hydroxylase which includes phosphorylated Ser 40.
Isotype IgG
Cross-Reactivity Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Characteristics Purified IgG
Purification Purified
Antigen
Alternative Name TYROSINE HYDROXYLASE (TH Antibody Abstract)
Gene ID 7054
UniProt P07101
Pathways Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Product cited in: Xiao, Xu, Tereshchenko, Novak, Schachner, Kleene: "Neural cell adhesion molecule modulates dopaminergic signaling and behavior by regulating dopamine D2 receptor internalization." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 47, pp. 14752-63, 2009 (PubMed).

Bevilaqua, Graham, Dunkley, von Nagy-Felsobuki, Dickson: "Phosphorylation of Ser(19) alters the conformation of tyrosine hydroxylase to increase the rate of phosphorylation of Ser(40)." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 40411-6, 2001 (PubMed).

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