CD3 antibody

Catalog No. ABIN2479815

The Mouse Monoclonal anti-CD3 antibody has been validated for FACS and IHC (fro). It is suitable to detect CD3 in samples from Human and Chimpanzee. There are 2+ publications available.

Quick Overview for CD3 antibody (ABIN2479815)

Target: CD3

Reactivity: Human, Chimpanzee

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: UCHT1

Product Details anti-CD3 Antibody

Cross-Reactivity: Chimpanzee

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

References for anti-CD3 antibody (ABIN2479815)

Hirsh, Manov, Cohen-Kaplan, Iancu: "Ultrastructural features of lymphocyte suppression induced by anthrax lethal toxin and treated with chloroquine." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 87, Issue 2, pp. 182-8, (2007) (PubMed).

Harding, Lipp, Alexander: "A therapeutic CD4 monoclonal antibody inhibits TCR-zeta chain phosphorylation, zeta-associated protein of 70-kDa Tyr319 phosphorylation, and TCR internalization in primary human T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 1, pp. 230-8, (2002) (PubMed).

Target Details for CD3

Target: CD3

Alternative Name: CD3

Gene ID: 916

UniProt: P07766

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway