HSPE1 antibody (AA 91-101) (APC)

Catalog No. ABIN2481930

This anti-HSPE1 antibody is a Rabbit Polyclonal antibody detecting HSPE1 in WB, ELISA, IHC, IP, IF and ICC. Suitable for Human.

Quick Overview for HSPE1 antibody (AA 91-101) (APC) (ABIN2481930)

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPE1 antibody is conjugated to APC

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-HSPE1 Antibody (APC)

Binding Specificity: AA 91-101

Specificity: Detects ~ 10 kDa.

Cross-Reactivity: Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus laevis

Purification: Protein A Purified

Immunogen: Human Cpn10 peptide AA 91-101

Application Details

Application Notes:

• WB (1:1000)
• IHC (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

1 μg/ml of ABIN2481930 was sufficient for detection of Cpn10 in 10 μg of Hela lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.3, 0.02 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for HSPE1

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Alternative Name: Cpn10

Background: Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10 kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process (1). Cpn10 has been located in human platelets, but is also present in human maternal serum (2, 3). It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy (4).

Gene ID: 3336

NCBI Accession: NP_002148

UniProt: P61604

Pathways: Positive Regulation of Endopeptidase Activity