CDC37 antibody (Atto 488)

Catalog No. ABIN2484516

This Rabbit Polyclonal antibody specifically detects CDC37 in WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for CDC37 antibody (Atto 488) (ABIN2484516)

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC37 antibody is conjugated to Atto 488

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CDC37 Antibody (Atto 488)

Specificity: Detects ~44.5 kDa.

Cross-Reactivity: Human

Purification: Protein A Purified

Immunogen: Native human Cdc37, full length

Application Details

Application Notes:

• WB (1:2000)
• ICC/IF (1:200)
• optimal dilutions for assays should be determined by the user.

Comment:

A 1:2000 dilution of ABIN2484516 was sufficient for detection of cdc37 in 20 μg of HeLa cell lysate by ECL immunoblot analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.68 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for CDC37

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Alternative Name: CDC37

Background: HSP90 co-chaperone Cdc37 is a protein that is encoded by the CDC37 gene. It has been found to form complexes with HSP90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK and elF-2 alpha kinases. It is thought to play a critical role in directing HSP90 to its target kinases (1, 2). CDC37 is necessary for maintaining prostate tumor cell growth and represents a novel target in the exploration for multi-targeted therapies (3, 4).

Gene ID: 11140

NCBI Accession: NP_008996

UniProt: Q16543