MSRB2 antibody (AA 31-130) (HRP)

Catalog No. ABIN2559525

The Rabbit Polyclonal anti-MSRB2 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect MSRB2 in samples from Mouse and Rat.

Quick Overview for MSRB2 antibody (AA 31-130) (HRP) (ABIN2559525)

Target: MSRB2 (Methionine Sulfoxide Reductase B2 (MSRB2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSRB2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MSRB2 Antibody (HRP)

Binding Specificity: AA 31-130

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MSRB2.

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MSRB2

Target: MSRB2 (Methionine Sulfoxide Reductase B2 (MSRB2))

Alternative Name: MSRB2

Background:

Synonyms: CBS1, MSRB, PILB, CBS-1, CGI-131, Methionine-R-sulfoxide reductase B2, mitochondrial, MsrB2

Background: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.

Gene ID: 22921

UniProt: Q9Y3D2