PRNP antibody (AA 143-159)

Catalog No. ABIN2627235

The Rabbit Polyclonal anti-PRNP antibody has been validated for WB, IHC and IHC (p). It is suitable to detect PRNP in samples from Rat and Mouse.

Quick Overview for PRNP antibody (AA 143-159) (ABIN2627235)

Target: PRNP (Prion Protein (PRNP))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRNP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PRNP Antibody

Binding Specificity: AA 143-159

Specificity: Highly expressed in the brain, lung, kidney and heart. Expressed at low levels in the liver and spleen. .

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse PRNP (143-159aa DWEDRYYRENMYRYPNQ), identical to the related rat sequence.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for PRNP

Target: PRNP (Prion Protein (PRNP))

Alternative Name: PRNP / PrP / Prion

Background: Name/Gene ID: PRNP

Synonyms: PRNP, AltPrP, ASCR, CD230 antigen, CJD, KURU, Major prion protein, p27-30, Prion, Prion-related protein, PRIP, Prion protein (p27-30), PrP, PrP33-35C, BSE, CD230, Prion protein, PrP27-30, PrPc

Gene ID: 5621

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation