Cryptosporidium antibody
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- Target
- Cryptosporidium
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Reactivity
- Cow
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Purification
- Sodium sulfate precipitation and ion exchange chromatography.
- Purity
- > 95 % pure
- Immunogen
- Oocysts purified from bovine feces
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- Application Notes
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ELISA. IFA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 4-5mg/mL (OD280nm, E0.1% = 1.4)
- Buffer
- 0.01 M PBS, pH 7.2. containing 0,09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Cryptosporidium
- Target Type
- Parasite
- Background
- Members of the genus Cryptosporidium are parasites of the intestinal tracts of fishes, reptiles, birds, and mammals. It seems that members of this genus do not display a high degree of host specificity, so the number of species in this genus remains a matter of some discussion. Cryptosporidium isolated from humans is now referred to as C. parvum. Cryptosporidium infections have been reported from a variety of wild and domesticated animals. Cryptosporidiosis is now recognized as an important opportunisitic infection, especially in immunocompromised hosts. Cryptosporidium is a small protozoan parasite, measuring about 3-5 μm. It lives on (or just under) the surface of the cells lining the small intestine, reproduces asexually, and oocysts are passed in the feces. Transmission of the infection occurs via the oocysts. Many human infections have been traced to the contamination of drinking water with oocysts from agricultural "run-off" (i.e., drainage from pastures), so it is considered a zoonosis. The most common symptom of cryptosporidiosis is watery diarrhea, other symptoms include stomach cramps or pain, fever, nausea and vomiting. In persons with healthy immune systems, symptoms usually last about 1 to 2 weeks.
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