PPP2R2B antibody (N-Term)

Catalog No. ABIN264942

Product Details anti-PPP2R2B Antibody

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Binding Specificity: AA 2-14, N-Term

Reactivity: Human, Rat, Mouse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2B antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to serine/threonine protein phosphatase 2A/B beta. Minimal cross reactivity against 2A/Bg .

Purification: Purified

Immunogen: Purified peptide conjugated to KLH corresponding to the sequence NH2-Cys-Gly-Glu-Glu- Asp-Ile-Asp-THr-Arg-Lys-Ile-Asn-Asn-Ser-Phe-COOH. This peptide antibody corresponds to N- terminal peptide of PP2A/Bb regulatory subunit having a MW of 53kDa. The sequence used is amino acid 2-14.

Isotype: IgG

Application Details

Application Notes: Immunoblotting: 1: 500 to 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.08 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for PPP2R2B

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Alternative Name: PPP2R2B (PPP2R2B Products)

Background: PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.Synonyms: B55-beta isoform, PP2A subunit B B-beta isoform, PR55-beta isoform, R2-beta isoform, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, protein phosphatase 2A 55 kDa regulatory subunit B beta

Gene ID: 5521

NCBI Accession: NP_001120853

UniProt: Q00005

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C