PPP2R2B antibody (Regulatory Subunit B)

Catalog No. ABIN7169246

Product Details anti-PPP2R2B Antibody

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Binding Specificity: AA 1-200, Regulatory Subunit B

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2B antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform protein (1-200AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP2R2B

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Alternative Name: PPP2R2B (PPP2R2B Products)

Synonyms: B55BETA antibody, PP2AB55BETA antibody, PP2ABBETA antibody, PP2APR55B antibody, PP2APR55BETA antibody, PR2AB55BETA antibody, PR2ABBETA antibody, PR2APR55BETA antibody, PR52B antibody, PR55-BETA antibody, PR55BETA antibody, SCA12 antibody, Pppr2b2 antibody, 2900026H06Rik antibody, 6330404L05Rik antibody, E130009M08Rik antibody, PP2A-PR55B antibody, PP2A antibody, ppp2r2b-a antibody, ppp2r2c antibody, ppp2r2b antibody, zgc:101861 antibody, PPP2R2B antibody, protein phosphatase 2 regulatory subunit Bbeta antibody, protein phosphatase 2, regulatory subunit B, beta antibody, protein phosphatase 2 regulatory subunit B, beta L homeolog antibody, protein phosphatase 2 regulatory subunit B, beta antibody, protein phosphatase 2, regulatory subunit B, beta b antibody, PPP2R2B antibody, Ppp2r2b antibody, ppp2r2b.L antibody, ppp2r2b antibody, ppp2r2bb antibody

Background:

Background: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity).

Aliases: 2ABB_HUMAN antibody, B55 beta antibody, Beta isoform of regulatory subunit B55 protein phosphatase 2 antibody, MGC24888 antibody, PP2A B55beta antibody, PP2A PR55B antibody, PP2A subunit B B beta isoform antibody, PP2A subunit B B55 beta isoform antibody, PP2A subunit B isoform B55 beta antibody, PP2A subunit B isoform B55-beta antibody, PP2A subunit B isoform beta antibody, PP2A subunit B isoform PR55 beta antibody, PP2A subunit B isoform PR55-beta antibody, PP2A subunit B isoform R2 beta antibody, PP2A subunit B isoform R2-beta antibody, PP2A subunit B PR55 beta isoform antibody, PP2A subunit B R2 beta isoform antibody, Ppp2r2b antibody, PR2AB beta antibody, PR2AB55 beta antibody, PR2APR55 beta antibody, PR52B antibody, PR55 beta antibody, Protein phosphatase 2 (formerly 2A) regulatory subunit B (PR 52) beta isoform antibody, Protein phosphatase 2 (formerly 2A) regulatory subunit B beta isoform antibody, Protein phosphatase 2 regulatory subunit B antibody, Protein phosphatase 2 regulatory subunit B beta isoform antibody, SCA 12 antibody, SCA12 antibody, Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform antibody, Serine/threonine protein phosphatase 2A neuronal isoform antibody, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform antibody

UniProt: Q00005

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C