UL84 (CMV UL84) antibody

Catalog No. ABIN265546

This Mouse Monoclonal antibody specifically detects in IF and WB. It exhibits reactivity toward Cytomegalovirus (CMV) and has been mentioned in 7+ publications.

Quick Overview for UL84 (CMV UL84) antibody (ABIN265546)

Target: UL84 (CMV UL84)

Reactivity: Cytomegalovirus (CMV)

Host: Mouse

Clonality: Monoclonal

Application: Immunofluorescence (IF), Western Blotting (WB)

Clone: MAB84

Product Details

Purification: Protein G agarose affinity chromatography

Isotype: IgG2a kappa

Application Details

Application Notes: Reactive with pUL84 of Cytomegalovirus in immunofluorescence (IFA) and western blot assays at 10 µg/mL.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/ml

Buffer: Phosphate Buffered Saline pH 7.4 (no azide)

Preservative: Azide free

Storage: -20 °C

References

Kim, Ahn: "Role of the specific interaction of UL112-113 p84 with UL44 DNA polymerase processivity factor in promoting DNA replication of human cytomegalovirus." in: Journal of virology, (2010) (PubMed).

Sanders, Clark, Morello, Spector: "Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses." in: Journal of virology, Vol. 82, Issue 14, pp. 7059-77, (2008) (PubMed).

Sanders, Del Rosario, White, Spector: "Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomes." in: Journal of virology, Vol. 82, Issue 22, pp. 11383-97, (2008) (PubMed).

Colletti, Smallenburg, Xu, Pari: "Human cytomegalovirus UL84 interacts with an RNA stem-loop sequence found within the RNA/DNA hybrid region of oriLyt." in: Journal of virology, Vol. 81, Issue 13, pp. 7077-85, (2007) (PubMed).

Gao, Colletti, Pari: "Identification of human cytomegalovirus UL84 virus- and cell-encoded binding partners by using proteomics analysis." in: Journal of virology, Vol. 82, Issue 1, pp. 96-104, (2007) (PubMed).

White, Del Rosario, Sanders, Spector: "The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus." in: Journal of virology, Vol. 81, Issue 6, pp. 2573-83, (2007) (PubMed).

Colletti, Xu, Cei, Tarrant, Pari: "Human cytomegalovirus UL84 oligomerization and heterodimerization domains act as transdominant inhibitors of oriLyt-dependent DNA replication: evidence that IE2-UL84 and UL84-UL84 interactions are required for lytic DNA replication." in: Journal of virology, Vol. 78, Issue 17, pp. 9203-14, (2004) (PubMed).

Target Details

Target: UL84 (CMV UL84)

Target Type: Viral Protein

Background: Mouse monoclonal antibody to UL84 of Cytomegalovirus. This antibody originates from ascites fluids and is purified by protein G agarose affinity chromatography