Asialo-GM1 antibody (Alexa Fluor 647)

Catalog No. ABIN2657115

This Rabbit Polyclonal antibody specifically detects Asialo-GM1 in FACS and IF. It exhibits reactivity toward All Species.

Quick Overview for Asialo-GM1 antibody (Alexa Fluor 647) (ABIN2657115)

Target: Asialo-GM1

Reactivity: All Species

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialo-GM1 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: Poly21460

Product Details anti-Asialo-GM1 Antibody (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for Asialo-GM1

Target: Asialo-GM1

Background: GM1 is a ganglioside, a type of glycosphingolipid with a single sialic acid group. Asialo-GM1 is a GM1 derivative without a sialic acid group. It is expressed on NK cells, basophils, monocytes/macrophages, and T cells. It is particularly expressed on very early thymocytes, but the expression decreases as the cells mature and become Thy-1 + . The highest expression is detected on neuronal tissues. This molecule has been shown to be involved in microbial pathogenesis. Antibodies specific for Asialo-GM1 are elevated in dementia, lupus, and Guillain-Barré syndrome.