Cadherin 5 antibody (Alexa Fluor 647)

Catalog No. ABIN2657127

This Rat Monoclonal antibody specifically detects Cadherin 5 in ICFC. It exhibits reactivity toward Mouse.

Quick Overview for Cadherin 5 antibody (Alexa Fluor 647) (ABIN2657127)

Target: Cadherin 5 (CDH5)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Cadherin 5 antibody is conjugated to Alexa Fluor 647

Application: Intracellular Flow Cytometry (ICFC)

Clone: BV13

Product Details anti-Cadherin 5 Antibody (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: CD144

Background: CD144, also known as vascular endothelial-cadherin (VE-cadherin), is a 120 kD member of the type II Cadherin family. It is an endothelial specific hemophilic adhesion molecule involved in endothelial cell survival, migration, contact-dependent growth inhibition, and homophilic adhesion. VE-cadherin is essential for maintaining the integrity of the endothelial barrier in vivo.

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2