CD3 antibody (Alexa Fluor 647)

Catalog No. ABIN2657163

This Mouse Monoclonal antibody specifically detects CD3 in FACS and ICFC. It exhibits reactivity toward Human.

Quick Overview for CD3 antibody (Alexa Fluor 647) (ABIN2657163)

Target: CD3

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: SK7

Product Details anti-CD3 Antibody (Alexa Fluor 647)

Cross-Reactivity: Chimpanzee

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CD3

Target: CD3

Alternative Name: CD3

Background: CD3ε is a 20 kD chain of the CD3/T-cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T-cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T cells, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway