CD38 antibody (Alexa Fluor 488)

Catalog No. ABIN2657415

This Rat Monoclonal antibody specifically detects CD38 in FACS and IHC. It exhibits reactivity toward Mouse.

Quick Overview for CD38 antibody (Alexa Fluor 488) (ABIN2657415)

Target: CD38

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD38 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: 9E1

Product Details anti-CD38 Antibody (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CD38

Target: CD38

Background: CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, subset of T cells, brain, muscle, and kidney. In the mouse, CD38 expression is downregulated on mouse germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.