CCR9 antibody (Alexa Fluor 647)

Catalog No. ABIN2657676

This Rat Monoclonal antibody specifically detects CCR9 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CCR9 antibody (Alexa Fluor 647) (ABIN2657676)

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CCR9 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: 9B1

Product Details anti-CCR9 Antibody (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CCR9

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Alternative Name: CD199

Background: CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells. It is expressed to a much lower level on spleen and lymph node cells. Expression of CCR9 on γ/δ T cells in the intraepithelial and small intestine has been reported. The interaction of CCR9 with its ligand CCL25 (TECK, thymus-expressed chemokine) may direct the trafficking of developing T cells in the thymus and generation of gut-specific immunological memory.