CD45RC antibody (Alexa Fluor 647)

Catalog No. ABIN2657805

This Mouse Monoclonal antibody specifically detects CD45RC in FACS. It exhibits reactivity toward Rat.

Quick Overview for CD45RC antibody (Alexa Fluor 647) (ABIN2657805)

Target: CD45RC

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD45RC antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: OX-22

Product Details anti-CD45RC Antibody (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CD45RC

Target: CD45RC

Alternative Name: CD45RC

Background: CD45RC is a 200-220 kD single chain type I membrane glycoprotein. It is an exon 5 splice variant (exon C) of the tyrosine phosphatase CD45. The CD45RC isoform is expressed on B cells, majority of CD8+ T cells and a subset of CD4+ T cells, but not on myeloid cells. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens, including CD1, CD2, CD3, and CD4. CD45 is involved in signaling lymphocytes activation.