Cadherin 5 antibody (PE-Cy7)

Catalog No. ABIN2659098

This Rat Monoclonal antibody specifically detects Cadherin 5 in WB, IHC, Neut, ICFC, CyTOF, ELISA (Capture) and ELISPOT (Capture). It exhibits reactivity toward Mouse.

Quick Overview for Cadherin 5 antibody (PE-Cy7) (ABIN2659098)

Target: Cadherin 5 (CDH5)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Cadherin 5 antibody is conjugated to PE-Cy7

Application: Western Blotting (WB), Immunohistochemistry (IHC), Neutralization (Neut), Intracellular Flow Cytometry (ICFC), Cytometry by Time of Flight (CyTOF), ELISA (Capture), ELISpot (Capture) (ELISPOT (Capture))

Clone: BV13

Product Details anti-Cadherin 5 Antibody (PE-Cy7)

Purification: The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: CD144

Background: CD144, also known as vascular endothelial-cadherin (VE-cadherin), is a 120 kD member of the type II Cadherin family. It is an endothelial specific hemophilic adhesion molecule involved in endothelial cell survival, migration, contact-dependent growth inhibition, and homophilic adhesion. VE-cadherin is essential for maintaining the integrity of the endothelial barrier in vivo.

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2