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L-Selectin antibody (Biotin)

The Rat Monoclonal anti-L-Selectin antibody has been validated for FACS. It is suitable to detect L-Selectin in samples from Rat.
Catalog No. ABIN2661120

Quick Overview for L-Selectin antibody (Biotin) (ABIN2661120)

Target

See all L-Selectin (SELL) Antibodies
L-Selectin (SELL) (Selectin L (SELL))

Reactivity

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Rat

Host

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Rat

Clonality

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Monoclonal

Conjugate

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This L-Selectin antibody is conjugated to Biotin

Application

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Flow Cytometry (FACS)

Clone

MEL-14
  • Purification

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    Isotype

    IgG2a kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    L-Selectin (SELL) (Selectin L (SELL))

    Alternative Name

    CD62L

    Target Type

    Chemical

    Background

    CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, glyCAM-1, and MAdCAM-1.
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