TCR V beta 7 antibody (FITC)

Catalog No. ABIN2662024

This Rat Monoclonal antibody specifically detects in ELISA (Capture). It exhibits reactivity toward Mouse.

Quick Overview for TCR V beta 7 antibody (FITC) (ABIN2662024)

Target: TCR V beta 7

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: FITC

Application: ELISA (Capture)

Clone: TR310

Product Details

Cross-Reactivity (Details): Mouse TCR Vβ7 bearing T cells and NKT cells, may not be present in mice expressing the MIS-1a haplotype

Characteristics: The TR310 antibody reacts with the mouse T cell receptor Vβ7 segment . T cells expressing the α/β T cell receptor use clonally distributed TCRs to recognize cell-bound antigens such as peptide/MHC complexes and viral superantigens. The α/β TCR is an oligomeric TCR complex composed of covalently bound α and β chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains. The TR310 antibody reacts with one such clonally distributed TCR β chain known as Vβ7. Vβ7 is expressed on a small subpopulation of both CD4+ and CD8+ T cells. The TR310 antibody has been used for the identification of Vβ7 expressing T cells by flow cytometry and immunoprecipitation.

Purification: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: TCR V beta 7

Alternative Name: TCR V Beta7