TCR V Alpha11.1 antibody (PE)

Catalog No. ABIN2662858

This Rat Monoclonal antibody specifically detects in FACS, IP and WB. It exhibits reactivity toward Mouse.

Quick Overview for TCR V Alpha11.1 antibody (PE) (ABIN2662858)

Target: TCR V Alpha11.1

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)

Clone: RR8-1

Product Details

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: TCR V Alpha11.1

Background: Vα11 T cell receptor (TCR Vα11) is a variant of TCR α chain and, along with TCR β chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition through the interaction with MHC-peptide complex to initiate the T cell-mediated immune responses. The RR8-1 antibody is specific for b and d haplotypes of TCR Vα11.1 and Vα11.2, but not for Vα11.3. It does not react with a and c haplotypes of TCR Vα11.