CD70 antibody (PE)

Catalog No. ABIN2663570

The Rat Monoclonal anti-CD70 antibody has been validated for WB and ELISA (Capture). It is suitable to detect CD70 in samples from Mouse.

Quick Overview for CD70 antibody (PE) (ABIN2663570)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD70 antibody is conjugated to PE

Application: Western Blotting (WB), ELISA (Capture)

Clone: FR70

Product Details anti-CD70 Antibody (PE)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background: CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.

Pathways: Cancer Immune Checkpoints