beta-2 Microglobulin antibody (beta-2-Microglobulin)

Details for Product anti-B2M Antibody No. ABIN2664068
Antigen
Reactivity
Human
487
100
67
64
16
9
6
4
3
2
2
2
1
1
1
1
1
1
Host
Mouse
323
195
15
11
9
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This beta-2 Microglobulin antibody is un-conjugated
50
34
18
18
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
3
2
1
1
1
1
1
Application
Flow Cytometry (FACS)
265
250
184
159
126
96
60
43
40
33
32
24
19
13
8
8
8
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Options
Clone 2M2
Isotype IgG1 kappa
Cross-Reactivity Pig (Porcine)
Purification The antibody was purified by affinity chromatography.
Antigen
Alternative Name Beta2-Microglobulin (B2M Antibody Abstract)
Background β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.
Pathways TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.
Supplier Images
Image no. 1 for anti-beta-2-Microglobulin (B2M) antibody (ABIN2664068) anti-beta-2-Microglobulin (B2M) antibody