CD213alpha2 antibody

Catalog No. ABIN2665962

This Mouse Monoclonal antibody specifically detects in FACS and IF. It exhibits reactivity toward Human.

Quick Overview for CD213alpha2 antibody (ABIN2665962)

Target: CD213alpha2

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 47

Product Details

Brand: Ultra-LEAF™

Purification: The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

Sterility: 0.2 μm filtered

Endotoxin Level:

Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Preservative: Azide free

Handling Advice: This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: CD213alpha2

Background: CD213α2, also known as IL13Rα2, is a type I transmembrane protein and member of the hematopoietin family. IL13R α2 is the high affinity receptor for IL-13, but it possibly acts as a decoy receptor to antagonize IL-13Rα 1/IL-4Ra-mediated IL-13 biological functions. IL13Rα2 is expressed by fibroblasts, smooth muscle cells, keratinocytes, and activated B cells. However, its presence on the cell surface is highly regulated. CD213α2 is also expressed in various types of cancer which makes it an attractive therapeutic target.