Asialo-GM1 antibody

Catalog No. ABIN2666025

This Rabbit Polyclonal antibody specifically detects Asialo-GM1 in FACS, IF, ICC, IP, IHC and WB. It exhibits reactivity toward All Species.

Quick Overview for Asialo-GM1 antibody (ABIN2666025)

Target: Asialo-GM1

Reactivity: All Species

Host: Rabbit

Clonality: Polyclonal

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)

Clone: Poly21460

Product Details anti-Asialo-GM1 Antibody

Brand: Ultra-LEAF™

Endotoxin Level:

Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid, Lyophilized

Preservative: Azide free

Handling Advice: This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for Asialo-GM1

Target: Asialo-GM1

Background: GM1 is a ganglioside, a type of glycosphingolipid with a single sialic acid group. Asialo-GM1 is a GM1 derivative without a sialic acid group. It is expressed on NK cells, basophils, monocytes/macrophages, and T cells. It is particularly expressed on very early thymocytes, but the expression decreases as the cells mature and become Thy-1 + . The highest expression is detected on neuronal tissues. This molecule has been shown to be involved in microbial pathogenesis. Antibodies specific for Asialo-GM1 are elevated in dementia, lupus, and Guillain-Barré syndrome.