Nanog antibody
Quick Overview for Nanog antibody (ABIN2666253)
Target
See all Nanog (NANOG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- The antibody was purified by affinity chromatography.
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Upon receipt, store undiluted at 4°C
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- Nanog (NANOG) (Nanog Homeobox (NANOG))
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Alternative Name
- Nanog
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Background
- Nanog is a transcription factor that plays key roles in the maintenance of pluripotency and self-renewal in embryonic stem cells. Nanog expression is regulated by other transcription factors, which include Sox2 and Oct-4. It also plays a role in epithelial malignancy and is enriched in cancer stem cells. The ablation of nanog is sufficient to reduce the cancer stem cell pool.
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Pathways
- Stem Cell Maintenance
Target
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