EIF2C3 antibody (AA 1-175)

Catalog No. ABIN2668249

There are 2+ publications for this product available. The Mouse Monoclonal anti-EIF2C3 antibody has been validated for ICC, IF and IP. It is suitable to detect EIF2C3 in samples from Human.

Quick Overview for EIF2C3 antibody (AA 1-175) (ABIN2668249)

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EIF2C3 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 4B1-F6

Product Details anti-EIF2C3 Antibody

Binding Specificity: AA 1-175

Purification: Protein G Chromatography

Immunogen: This Ago3 (Argonaute 3) antibody was raised against a recombinant protein corresponding to amino acids 1-175 of human Ago3.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-EIF2C3 antibody (ABIN2668249)

Shang, Zhang, Xu, Xi, Zhang, Wang, Wu: "Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects." in: Nature communications, Vol. 6, pp. 8430, (2015) (PubMed).

Azuma-Mukai, Oguri, Mituyama, Qian, Asai, Siomi, Siomi: "Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 23, pp. 7964-9, (2008) (PubMed).

Target Details for EIF2C3

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Alternative Name: Ago3

Molecular Weight: 110 kDa

Gene ID: 192669

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway