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Histone 3 antibody (H3K18ac)

This Rabbit Polyclonal antibody specifically detects Histone 3 in WB, IF, ChIP, DB, ICC and ChIP-seq. It exhibits reactivity toward Human and has been mentioned in 3+ publications.
Catalog No. ABIN2668428

Quick Overview for Histone 3 antibody (H3K18ac) (ABIN2668428)

Target

See all Histone 3 (H3) Antibodies
Histone 3 (H3) (Histone H3 (H3))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Histone 3 antibody is un-conjugated

Application

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Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq)
  • Binding Specificity

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    H3K18ac

    Purification

    Protein A Chromatography

    Immunogen

    This Histone H3 acetylLys18 antibody was raised against a peptide including acetyllysine 18 of histone H3.

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    1 μg/μL

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Storage

    -20 °C

    Storage Comment

    Antibodies in solution can be stored at -20 °C for 2 years.

    Expiry Date

    6 months
  • Zhang, Li, Rezaeian, Xu, Chou, Jin, Han, Pan, Wang, Long, Zhang, Huang, Tsai, Tsai, Logothetis, Lin: "H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis." in: Nature communications, Vol. 8, pp. 14799, (2017) (PubMed).

    Yasuma, Yasunaga, Takemoto, Sugata, Mitobe, Takenouchi, Nakagawa, Suzuki, Matsuoka: "HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)." in: PLoS pathogens, Vol. 12, Issue 1, pp. e1005372, (2016) (PubMed).

    Cohen, Friedmann, Hwang, Marmorstein, Lee: "The microtubule-associated tau protein has intrinsic acetyltransferase activity." in: Nature structural & molecular biology, Vol. 20, Issue 6, pp. 756-62, (2013) (PubMed).

  • Target

    Histone 3 (H3) (Histone H3 (H3))

    Alternative Name

    Histone H3

    Molecular Weight

    17 kDa

    Gene ID

    3020
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