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Histone 3 antibody (H3K4me3)

H3 Reactivity: Human, Mouse, Saccharomyces cerevisiae WB, IF, ChIP, DB, ChIP-seq, ICC, CUT&RUN, CUT&Tag Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2668472
  • Target See all Histone 3 (H3) Antibodies
    Histone 3 (H3)
    Binding Specificity
    • 62
    • 47
    • 45
    • 43
    • 42
    • 37
    • 36
    • 35
    • 35
    • 35
    • 34
    • 32
    • 32
    • 31
    • 29
    • 29
    • 26
    • 25
    • 24
    • 23
    • 23
    • 22
    • 20
    • 18
    • 18
    • 17
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 14
    • 13
    • 13
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 10
    • 10
    • 10
    • 10
    • 9
    • 8
    H3K4me3
    Reactivity
    • 1412
    • 941
    • 861
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 29
    • 29
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Saccharomyces cerevisiae
    Host
    • 1227
    • 246
    • 8
    • 4
    Rabbit
    Clonality
    • 1127
    • 357
    • 1
    Polyclonal
    Conjugate
    • 827
    • 81
    • 63
    • 63
    • 63
    • 62
    • 62
    • 62
    • 37
    • 33
    • 23
    • 17
    • 17
    • 17
    • 17
    • 17
    • 14
    • 7
    • 2
    • 1
    This Histone 3 antibody is un-conjugated
    Application
    • 893
    • 392
    • 381
    • 318
    • 254
    • 188
    • 182
    • 181
    • 166
    • 160
    • 141
    • 126
    • 118
    • 48
    • 38
    • 34
    • 32
    • 20
    • 15
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), ChIP DNA-Sequencing (ChIP-seq), Immunocytochemistry (ICC), Cleavage Under Targets and Release Using Nuclease (CUT&RUN), Cleavage Under Targets and Tagmentation (CUT&Tag)
    Purification
    None
    Immunogen
    This Histone H3 trimethylLys4 antibody was raised against a peptide including trimethyllysine 4 of histone H3.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Storage
    -20 °C
    Storage Comment
    Antibodies in solution can be stored at -20 °C for 2 years.
    Expiry Date
    6 months
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    Brahma, Henikoff: "RSC-Associated Subnucleosomes Define MNase-Sensitive Promoters in Yeast." in: Molecular cell, Vol. 73, Issue 2, pp. 238-249.e3, (2019) (PubMed).

    Pan, Guan, Liu, Li, Wang, Wu, Zhou, Zhang, Ren, Zhang, Li, Yang, Hao, Yuan, Yuan, Wang, Ju, Mao, Li, Qu, Tang, Liu: "SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2." in: Cell research, Vol. 26, Issue 2, pp. 190-205, (2016) (PubMed).

    Toth, Papp, Brulois, Choi, Gao, Jung: "LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection." in: PLoS pathogens, Vol. 12, Issue 9, pp. e1005878, (2016) (PubMed).

    Lowe, Gemma, Rakyan, Holland: "Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development." in: BMC genomics, Vol. 16, pp. 295, (2015) (PubMed).

    Weirich, Kudithipudi, Kycia, Jeltsch: "Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme." in: Clinical epigenetics, Vol. 7, Issue 1, pp. 36, (2015) (PubMed).

    Valdez, Li, Murray, Ji, Liu, Popat, Champlin, Andersson: "Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators." in: Experimental hematology, Vol. 43, Issue 6, pp. 448-61.e2, (2015) (PubMed).

    Brown, Esterhazy, Sarde, London, Pullabhatla, Osma-Garcia, Al-Bader, Ortiz, Elgueta, Arno, de Rinaldis, Mucida, Lord, Noelle: "Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program." in: Immunity, Vol. 42, Issue 3, pp. 499-511, (2015) (PubMed).

    Sabò, Kress, Pelizzola, de Pretis, Gorski, Tesi, Morelli, Bora, Doni, Verrecchia, Tonelli, Fagà, Bianchi, Ronchi, Low, Müller, Guccione, Campaner, Amati: "Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis." in: Nature, Vol. 511, Issue 7510, pp. 488-92, (2014) (PubMed).

    Fereres, Simón, Mohd-Sarip, Verrijzer, Busturia: "dRYBP counteracts chromatin-dependent activation and repression of transcription." in: PLoS ONE, Vol. 9, Issue 11, pp. e113255, (2014) (PubMed).

    Putiri, Tiedemann, Liu, Choi, Robertson: "Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome." in: Oncotarget, Vol. 5, Issue 15, pp. 6338-52, (2014) (PubMed).

    Dhimolea, Wadia, Murray, Settles, Treitman, Sonnenschein, Shioda, Soto: "Prenatal exposure to BPA alters the epigenome of the rat mammary gland and increases the propensity to neoplastic development." in: PLoS ONE, Vol. 9, Issue 7, pp. e99800, (2014) (PubMed).

    Konsavage, Yochum: "The myc 3' wnt-responsive element suppresses colonic tumorigenesis." in: Molecular and cellular biology, Vol. 34, Issue 9, pp. 1659-69, (2014) (PubMed).

    Asmar, Hother, Kulosman, Treppendahl, Nielsen, Ralfkiaer, Pedersen, Møller, Ralfkiaer, de Nully Brown, Grønbæk: "Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another "double hit" lymphoma with very poor outcome?" in: Oncotarget, Vol. 5, Issue 7, pp. 1912-25, (2014) (PubMed).

    DAnselmi, Masiello, Cucina, Proietti, Dinicola, Pasqualato, Ricci, Dobrowolny, Catizone, Palombo, Bizzarri: "Microenvironment promotes tumor cell reprogramming in human breast cancer cell lines." in: PLoS ONE, Vol. 8, Issue 12, pp. e83770, (2014) (PubMed).

    Kelso, Baumgart, Eickhoff, Albert, Antrecht, Lemcke, Klebl, Meisterernst: "Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3675-88, (2014) (PubMed).

    Belyea, Xu, Pentz, Medrano, Li, Hu, Turner, Legallo, Jones, Tario, Liang, Gross, Sequeira-Lopez, Gomez: "Identification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia." in: Nature communications, Vol. 5, pp. 3273, (2014) (PubMed).

    Amatori, Ballarini, Faversani, Belloni, Fusar, Bosari, Pelicci, Minucci, Fanelli: "PAT-ChIP coupled with laser microdissection allows the study of chromatin in selected cell populations from paraffin-embedded patient samples." in: Epigenetics & chromatin, Vol. 7, pp. 18, (2014) (PubMed).

    Kumar, Duester: "Retinoic acid controls body axis extension by directly repressing Fgf8 transcription." in: Development (Cambridge, England), Vol. 141, Issue 15, pp. 2972-7, (2014) (PubMed).

    Rafehi, Balcerczyk, Lunke, Kaspi, Ziemann, Kn, Okabe, Khurana, Ooi, Khan, Du, Chang, Haviv, Keating, Karagiannis, El-Osta: "Vascular histone deacetylation by pharmacological HDAC inhibition." in: Genome research, Vol. 24, Issue 8, pp. 1271-84, (2014) (PubMed).

  • Target
    Histone 3 (H3)
    Alternative Name
    Histone H3 (H3 Products)
    Synonyms
    H-3 antibody, histocompatibility 3 antibody, H3 antibody
    Molecular Weight
    17 kDa
    Gene ID
    3020
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