Retinoic Acid Receptor alpha antibody (AA 420-443)

Catalog No. ABIN2668711

The Mouse Monoclonal anti-Retinoic Acid Receptor alpha antibody has been validated for WB, IHC, ELISA, IP, ICC and EMSA. It is suitable to detect Retinoic Acid Receptor alpha in samples from Human and Mouse. There are 2+ publications available.

Quick Overview for Retinoic Acid Receptor alpha antibody (AA 420-443) (ABIN2668711)

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoic Acid Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Electrophoretic Mobility-Shift Assay (EMSA)

Clone: 9alpha-9A6

Product Details anti-Retinoic Acid Receptor alpha Antibody

Binding Specificity: AA 420-443

Purification: Protein G Chromatography

Immunogen: This RAR-a antibody was raised against a recombinant protein corresponding to amino acids 420-443 (the F region) of human RARa.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.71 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-Retinoic Acid Receptor alpha antibody (ABIN2668711)

Quere, Baudet, Cassinat, Bertrand, Marti, Manchon, Piquemal, Chomienne, Commes: "Pharmacogenomic analysis of acute promyelocytic leukemia cells highlights CYP26 cytochrome metabolism in differential all-trans retinoic acid sensitivity." in: Blood, Vol. 109, Issue 10, pp. 4450-60, (2007) (PubMed).

Reichrath, Mittmann, Kamradt, Müller: "Expression of retinoid-X receptors (-alpha,-beta,-gamma) and retinoic acid receptors (-alpha,-beta,-gamma) in normal human skin: an immunohistological evaluation." in: The Histochemical journal, Vol. 29, Issue 2, pp. 127-33, (1997) (PubMed).

Target Details for Retinoic Acid Receptor alpha

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Alternative Name: RAR-alpha

Molecular Weight: 52 kDa

Gene ID: 5914

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins