Multidrug-Resistance Like Protein 1 antibody

Catalog No. ABIN2689852

Cited in 2+ publications. This anti-Multidrug-Resistance Like Protein 1 antibody is a Mouse Monoclonal antibody detecting Multidrug-Resistance Like Protein 1 in ICS. Suitable for Human.

Quick Overview for Multidrug-Resistance Like Protein 1 antibody (ABIN2689852)

Target: Multidrug-Resistance Like Protein 1 (MRP)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Multidrug-Resistance Like Protein 1 antibody is un-conjugated

Application: Intracellular Staining (ICS)

Clone: QCRL

Product Details anti-Multidrug-Resistance Like Protein 1 Antibody

Characteristics: Reacts with an intracellular epitope of the multidrug resistance protein (MRP1). MRP1 is a 190 kDa integral membrane phosphoglycoprotein, member of the ATP-binding cassette transporter proteins, overexpressed in some drug-selected resistant cell lines and has been shown to cause multidrug resistance in transfected cells.

BD Pharmingen™ Purified Mouse Anti-Human MRP1 - Purified - Clone QCRL-3 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-Multidrug-Resistance Like Protein 1 antibody (ABIN2689852)

Hipfner, Gauldie, Deeley, Cole: "Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies." in: Cancer research, Vol. 54, Issue 22, pp. 5788-92, (1994) (PubMed).

Cole, Bhardwaj, Gerlach, Mackie, Grant, Almquist, Stewart, Kurz, Duncan, Deeley: "Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line." in: Science (New York, N.Y.), Vol. 258, Issue 5088, pp. 1650-4, (1993) (PubMed).

Target Details for Multidrug-Resistance Like Protein 1

Target: Multidrug-Resistance Like Protein 1 (MRP)

Alternative Name: MRP1