ACD antibody

Catalog No. ABIN2715647

This Mouse Monoclonal antibody specifically detects ACD in WB and IF. It exhibits reactivity toward Human.

Quick Overview for ACD antibody (ABIN2715647)

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 1C8

Product Details anti-ACD Antibody

Characteristics: Homo sapiens adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ACD(NP_001075955) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:2000, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ACD

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Alternative Name: ACD

Background: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

Molecular Weight: 57.6 kDa

Gene ID: 65057

NCBI Accession: NM_001082486

HGNC: 65057

Pathways: Telomere Maintenance