Aquaporin 1 antibody

Catalog No. ABIN2716313

This anti-Aquaporin 1 antibody is a Mouse Monoclonal antibody detecting Aquaporin 1 in WB, IHC, IF and FACS. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Aquaporin 1 antibody (ABIN2716313)

Target: Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aquaporin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 2D10

Product Details anti-Aquaporin 1 Antibody

Characteristics: Homo sapiens aquaporin 1 (Colton blood group) (AQP1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human AQP1 (NP_932766) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Aquaporin 1 antibody (ABIN2716313)

Vieceli Dalla Sega, Zambonin, Fiorentini, Rizzo, Caliceti, Landi, Hrelia, Prata: "Specific aquaporins facilitate Nox-produced hydrogen peroxide transport through plasma membrane in leukaemia cells." in: Biochimica et biophysica acta, Vol. 1843, Issue 4, pp. 806-14, (2014) (PubMed).

Target Details for Aquaporin 1

Target: Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))

Alternative Name: AQP1

Background: Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 28.3 kDa

Gene ID: 358

NCBI Accession: NM_198098

HGNC: 358

Pathways: Hormone Transport