Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

EIF4E antibody

EIF4E Reactivity: Human WB, FACS Host: Mouse Monoclonal 6C11 unconjugated
Catalog No. ABIN2720090
  • Target See all EIF4E Antibodies
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Reactivity
    • 122
    • 61
    • 49
    • 19
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 106
    • 15
    • 2
    Mouse
    Clonality
    • 99
    • 24
    Monoclonal
    Conjugate
    • 57
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This EIF4E antibody is un-conjugated
    Application
    • 96
    • 51
    • 41
    • 27
    • 27
    • 26
    • 16
    • 15
    • 14
    • 13
    • 7
    • 6
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Characteristics
    Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Full length human recombinant protein of human EIF4E (NP_001959) produced in HEK293T cell.
    Clone
    6C11
    Isotype
    IgG1
    Top Product
    Discover our top product EIF4E Primary Antibody
  • Application Notes
    WB 1:500~2000, FLOW 1:100
    Comment

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Alternative Name
    EIF4E (EIF4E Products)
    Background
    All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G (MIM 600495) (Rychlik et al., 1987 [PubMed 3469651]).
    Molecular Weight
    24.9 kDa
    Gene ID
    1977
    NCBI Accession
    NM_001968
    HGNC
    1977
    Pathways
    BCR Signaling
Support