Frataxin antibody
Quick Overview for Frataxin antibody (ABIN2721399)
Target
See all Frataxin (FXN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Homo sapiens frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1
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Purification
- Purified from mouse ascites fluids by affinity chromatography
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Immunogen
- Full length human recombinant protein of human FXN(NP_000135) produced in HEK293T cell.
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Isotype
- IgG1
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Application Notes
- WB 1:1000, IHC 1:150, IF 1:100, FLOW 1:100,
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Comment
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The concentration of the product may vary between diferrent lots.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- Frataxin (FXN)
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Alternative Name
- FXN
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Background
- This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 18.8 kDa
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Gene ID
- 2395
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NCBI Accession
- NM_000144
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HGNC
- 2395
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Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
Target
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