LCMT1 antibody

Catalog No. ABIN2724546

This Mouse Monoclonal antibody specifically detects LCMT1 in WB, FACS, IHC and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for LCMT1 antibody (ABIN2724546)

Target: LCMT1 (Leucine Carboxyl Methyltransferase 1 (LCMT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LCMT1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 1G5

Product Details anti-LCMT1 Antibody

Characteristics: Homo sapiens leucine carboxyl methyltransferase 1 (LCMT1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human LCMT1(NP_057393) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-LCMT1 antibody (ABIN2724546)

Tang, Qin, Wang, Liang, Cai, Mo, Huang, Liang, Wei, Ao, Xu, Liu, Xiao, Guo, Lu, Li: "H2 O2 induces PP2A demethylation to downregulate mTORC1 signaling in HEK293 cells." in: Cell biology international, (2018) (PubMed).

Target Details for LCMT1

Target: LCMT1 (Leucine Carboxyl Methyltransferase 1 (LCMT1))

Alternative Name: LCMT1

Background: LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA, MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).

Molecular Weight: 38.2 kDa

Gene ID: 51451

NCBI Accession: NM_016309

HGNC: 51451