PSMB9 antibody (AA 21-219)

Catalog No. ABIN2729947

The Mouse Monoclonal anti-PSMB9 antibody has been validated for WB, IHC, FACS and IF. It is suitable to detect PSMB9 in samples from Human.

Quick Overview for PSMB9 antibody (AA 21-219) (ABIN2729947)

Target: PSMB9 (Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSMB9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 1D1

Product Details anti-PSMB9 Antibody

Binding Specificity: AA 21-219

Characteristics: Homo sapiens proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (PSMB9)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 21-219 of human PSMB9(NP_002791) produced in E.coli.

Isotype: IgG2a

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PSMB9

Target: PSMB9 (Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9))

Alternative Name: PSMB9

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.

Molecular Weight: 23.1 kDa

Gene ID: 5698

NCBI Accession: NM_002800

HGNC: 5698

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA