SHPK antibody

Catalog No. ABIN2731602

Product Details anti-SHPK Antibody

Target: SHPK (Sedoheptulokinase (SHPK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SHPK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Homo sapiens sedoheptulokinase (SHPK)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SHPK(NP_037408) produced in HEK293T cell.

Clone: 3D7

Isotype: IgG1

Application Details

Application Notes: WB 1:500, IHC 1:150, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SHPK

Target: SHPK (Sedoheptulokinase (SHPK))

Alternative Name: SHPK (SHPK Products)

Background: The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. COMPLETENESS: complete on the 3' end.

Molecular Weight: 51.3 kDa

Gene ID: 23729

NCBI Accession: NM_013276

HGNC: 23729

Pathways: Cellular Response to Molecule of Bacterial Origin