SH2B3 antibody

Catalog No. ABIN2731950

The Mouse Monoclonal anti-SH2B3 antibody (Clone 2D8) (ABIN2731950) specifically detects SH2B3 in WB, IHC, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for SH2B3 antibody (ABIN2731950)

Target: SH2B3 (SH2B Adaptor Protein 3 (SH2B3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SH2B3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 2D8

Product Details anti-SH2B3 Antibody

Characteristics: Homo sapiens SH2B adaptor protein 3 (SH2B3)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SH2B3 (NP_005466) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SH2B3

Target: SH2B3 (SH2B Adaptor Protein 3 (SH2B3))

Alternative Name: SH2B3

Background: This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

Molecular Weight: 63 kDa

Gene ID: 10019

NCBI Accession: NM_005475

HGNC: 10019