CD5 antibody

Catalog No. ABIN2739563

This Mouse Monoclonal antibody specifically detects CD5 in FACS, IHC, IF, IP, ELISA and IHC (fro). It exhibits reactivity toward Human and Rhesus Monkey.

Quick Overview for CD5 antibody (ABIN2739563)

Target: CD5

Reactivity: Human, Rhesus Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD5 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CRIS-1

Product Details anti-CD5 Antibody

Specificity: Human CD5

Purification: Protein G purified

Immunogen: Stimulated human leukocytes were used as the immunogen for this CD5 antibody.

Type of Immunogen: Cells

Isotype: IgG2a kappa

Application Details

Application Notes: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IP

Usage: This antibody recognizes a 67  kDa transmembrane protein, which is identified as CD5. It is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in Tcell areas. CD5 antibody is a pan Tcell marker that also reacts with a range of neoplastic Bcells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large Bcell lymphoma. Aberrant expression is useful in making a diagnosis of mature Tcell neoplasms. CD5 antibody detection is diagnostic in CLL/SLL within a panel of other Bcell markers, especially one that includes anti-CD23. CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, it can be used in distinguishing thymic carcinoma (+) from thymoma (-). It does not react with granulocytes or monocytes. ELISA: Order BSA-free format for coating.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for CD5

Target: CD5

Alternative Name: CD5

Background: Name/Gene ID: CD5

Synonyms: CD5, CD5 antigen, CD5 antigen (p56-62), CD5 Molecule, Lymphocyte antigen T1/Leu-1, LEU1, T1

Gene ID: 921