OPTN antibody (AA 241-577)

Catalog No. ABIN2743402

This Rabbit Polyclonal antibody specifically detects OPTN in WB, IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for OPTN antibody (AA 241-577) (ABIN2743402)

Target: OPTN (Optineurin (OPTN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPTN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-OPTN Antibody

Binding Specificity: AA 241-577

Specificity: Present in aqueous humor of the eye (at protein level). Highly expressed in trabecular meshwork. Expressed nonpigmented ciliary epithelium, retina, brain, adrenal cortex, fetus, lymphocyte, fibroblast, skeletal muscle, heart, liver, brain and placenta. .

Purification: Immunogen affinity purified

Immunogen: E.coli-derived human Optineurin recombinant protein (Position: R241-I577). Human Optineurin shares 82% amino acid (aa) sequence identity with both mouse and rat Optineurin.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from 5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for OPTN

Target: OPTN (Optineurin (OPTN))

Alternative Name: OPTN / Optineurin

Background: Name/Gene ID: OPTN

Synonyms: OPTN, ALS12, E3-14.7K-interacting protein, FIP-2, HIP-7, HYPL, Huntingtin yeast partner L, HIP7, TFIIIA-INTP, NEMO-related protein, NRP, Optineurin, FIP2, GLC1E

Gene ID: 10133

Pathways: M Phase