PSCA antibody (AA 21-95)
Quick Overview for PSCA antibody (AA 21-95) (ABIN2743866)
Target
See all PSCA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 21-95
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Specificity
- Highly expressed in prostate (basal, secretory and neuroendocrine epithelium cells). Also found in bladder (transitional epithelium), placenta (trophoblasts), stomach (neuroendocrine cells), colon (neuroendocrine cells) and kidney (collecting ducts). Overexpressed in prostate cancers and expression is correlated with tumor stage, grade and androgen- independence. Highly expressed in prostate cancer bone metastases. Expressed in gastric epithelial cells, mainly in the isthmus (at protein level). Not detected in normal intestinal epithelium (at protein level). .
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Purification
- Immunogen affinity purified
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Immunogen
- E.coli-derived human PSCA recombinant protein (Position: L21-S95). Human PSCA shares 66% amino acid (aa) sequence identity with mouse PSCA.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Distilled water
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Concentration
- Lot specific
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Buffer
- Lyophilized from 5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze thaw cycles
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Storage
- 4 °C,-20 °C
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Storage Comment
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
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- PSCA (Prostate Stem Cell Antigen (PSCA))
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Alternative Name
- PSCA
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Background
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Name/Gene ID: PSCA
Synonyms: PSCA, Prostate stem cell antigen, PRO232 -
Gene ID
- 8000
Target
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